Nutritional immunity: transition metals at the pathogen-host interface.
Abstract
Transition metals occupy an essential niche in biological systems. Their electrostatic properties stabilize substrates or reaction intermediates in the active sites of enzymes, and their heightened reactivity is harnessed for catalysis. However, this heightened activity also renders transition metals toxic at high concentrations. Bacteria, like all living organisms, must regulate their intracellular levels of these elements to satisfy their...
Paper Details
Title
Nutritional immunity: transition metals at the pathogen-host interface.
Published Date
Jul 16, 2012
Journal
Volume
10
Issue
8
Pages
525 - 537
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Notes
History