Central nervous system involvement with multiple myeloma: long term survival can be achieved with radiation, intrathecal chemotherapy, and immunomodulatory agents

Summary Involvement of the central nervous system ( CNS ) in multiple myeloma ( MM ) is a rare complication, with reported survival of <6 months. This report describes 37 MM patients with leptomeningeal and/or parenchymal brain involvement treated at our institution and identifies factors associated with long‐term survival. From J anuary 1999 to D ecember 2010, 37 patients with CNS MM were evaluated at our institution. Clinical...