A Distinct Function of Regulatory T Cells in Tissue Protection
Abstract
Regulatory T (Treg) cells suppress immune responses to a broad range of non-microbial and microbial antigens and indirectly limit immune inflammation-inflicted tissue damage by employing multiple mechanisms of suppression. Here, we demonstrate that selective Treg cell deficiency in amphiregulin leads to severe acute lung damage and decreased blood oxygen concentration during influenza virus infection without any measureable alterations in Treg...
Paper Details
Title
A Distinct Function of Regulatory T Cells in Tissue Protection
Published Date
Aug 1, 2015
Journal
Volume
162
Issue
5
Pages
1078 - 1089
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