Genetic basis of virulence in Shigella species
Abstract
Shigella species and enteroinvasive strains of Escherichia coli cause disease by invasion of the colonic epithelium, and this invasive phenotype is mediated by genes carried on 180- to 240-kb plasmids. In addition, at least eight loci on the Shigella chromosome are necessary for full expression of virulence. The products of these genes can be classified as (i) virulence determinants that directly affect the ability of shigellae to survive in the...
Paper Details
Title
Genetic basis of virulence in Shigella species
Published Date
Jun 1, 1991
Journal
Volume
55
Issue
2
Pages
206 - 224
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History