Candidate DNA repair susceptibility genes identified by exome sequencing in high-risk pancreatic cancer

Volume: 370, Issue: 2, Pages: 302 - 312
Published: Jan 1, 2016
Abstract
The genetic basis underlying the majority of hereditary pancreatic adenocarcinoma (PC) is unknown. Since DNA repair genes are widely implicated in gastrointestinal malignancies, including PC, we hypothesized that there are novel DNA repair PC susceptibility genes. As germline DNA repair gene mutations may lead to PC subtypes with selective therapeutic responses, we also hypothesized that there is an overall survival (OS) difference in mutation...
Paper Details
Title
Candidate DNA repair susceptibility genes identified by exome sequencing in high-risk pancreatic cancer
DOI
Published Date
Jan 1, 2016
Journal
Volume
370
Issue
2
Pages
302 - 312
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