Detailed analysis of Helicobacter pylori Fur‐regulated promoters reveals a Fur box core sequence and novel Fur‐regulated genes

Summary In Helicobacter pylori , iron balance is controlled by the Ferric uptake regulator (Fur), an iron‐sensing repressor protein that typically regulates expression of genes implicated in iron transport and storage. Herein, we carried out extensive analysis of Fur‐regulated promoters and identified a 7‐1‐7 motif with dyad symmetry (5′‐TAATAATnATTATTA‐3′), which functions as the Fur box core sequence of H. pylori . Addition of this sequence to...