Radiolabelled GLP‐1 analogues for in vivo targeting of insulinomas
Abstract
Internalizing agonists are usually selected for peptide receptor targeting. There is increasing evidence that non‐internalizing receptor antagonists can be used for this purpose. We investigated whether the glucagon‐like peptide‐1 receptor (GLP‐1R) antagonist exendin(9–39) can be used for in vivo targeting of GLP‐1R expressing tumours and compared the in vitro and in vivo characteristics with the GLP‐1R agonists exendin‐3 and exendin‐4. The...
Paper Details
Title
Radiolabelled GLP‐1 analogues for in vivo targeting of insulinomas
Published Date
Mar 1, 2012
Volume
7
Issue
2
Pages
160 - 166
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