Human Breast Cancer Invasion and Aggression Correlates with ECM Stiffening and Immune Cell Infiltration

Volume: 7, Issue: 10, Pages: 1120 - 1134
Published: Oct 5, 2015
Abstract
Tumors are stiff and data suggest that the extracellular matrix stiffening that correlates with experimental mammary malignancy drives tumor invasion and metastasis. Nevertheless, the relationship between tissue and extracellular matrix stiffness and human breast cancer progression and aggression remains unclear. We undertook a biophysical and biochemical assessment of stromal–epithelial interactions in noninvasive, invasive and normal adjacent...
Paper Details
Title
Human Breast Cancer Invasion and Aggression Correlates with ECM Stiffening and Immune Cell Infiltration
Published Date
Oct 5, 2015
Volume
7
Issue
10
Pages
1120 - 1134
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