Analysis of loco-regional failures in head and neck cancer after radical radiation therapy

To investigate the anatomical distribution of loco-regional treatment failures (LRF) in patients with head and neck squamous cell carcinoma (HNSCC) in relation to clinical target volume (CTV) delineation. 56 patients with LRF were retrospectively identified. Patients were previously treated with radical intensity modulated radiotherapy (IMRT) +/− chemotherapy. Target volumes include gross tumour volume (GTV), its volumetric expansion of 10 mm...