Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy
Abstract
Background: In lung cancer, the efficacy of conventional chemotherapy is limited due to poor drug accumulation in tumors and nonspecific cytotoxicity. Resolving these issues will increase therapeutic efficacy. Methods: GNR-Dox-Tf-NPs (gold nanorod-doxorubicin-transferrin-nanoparticles) were prepared by different chemical approaches. The efficacy of these nanoparticles was carried out by cell viability in lung cancer and primary coronary artery...
Paper Details
Title
Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy
Published Date
Oct 1, 2015
Pages
6773 - 6773
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