Familial Adenomatous Polyposis–Associated, Cribriform Morular Variant of Papillary Thyroid Carcinoma Harboring a K-RAS Mutation: Case Presentation and Review of Molecular Mechanisms

The cribriform morular variant of papillary thyroid carcinoma (CMVPTC) is a rare subtype of papillary thyroid cancer that occurs most often in association with the familial adenomatous polyposis (FAP) syndrome.A 18-year-old woman presented with recurrence of PTC in her neck. She had a prior diagnosis of FAP syndrome. Review of her original pathology slides reclassified the case as a CMVPTC. The tumor was examined for the four most common...