Reduction of peak oxygen consumption in patients with non-small cell lung cancer treated with neoadjuvant chemotherapy

Background null Fitness is best assessed with cardiopulmonary exercise testing (CPET) in patients with non-small cell lung cancer (NSCLC) eligible for lung resection surgery. Peak oxygen consumption (VO2 peak) is predictive of short-term complications after elective thoracic surgery. Anti-neoplastic drugs have toxic effects on cellular metabolism and therefore on VO2 peak. Effect of neoadjuvant chemotherapy on cardiopulmonary fitness has...