Characterization and evaluation of pre-clinical suitability of a syngeneic orthotopic mouse ovarian cancer model.
Abstract
To develop and characterize the pre-clinical suitability of a syngeneic mouse epithelial ovarian cancer model in immunocompetent hosts.ID8 mouse ovarian surface epithelium cells were implanted into the left ovarian bursa of C57BL/6 mice. Using conventional as well as ultrasound-based techniques and histopathological analysis, the tumor weights, volumes, metastases, ascites and vascularity were observed over a period of 16 weeks.Ovarian weights...
Paper Details
Title
Characterization and evaluation of pre-clinical suitability of a syngeneic orthotopic mouse ovarian cancer model.
Published Date
Apr 1, 2013
Journal
Volume
33
Issue
4
Pages
1317 - 24
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