Impact of Various Parameters in Detecting Chromosomal Aberrations by FISH to Describe Radiosensitivity

Analysis of radiation-induced chromosomal aberrations is regarded as the “gold standard” for classifying individual radiosensitivity. A variety of different parameters can be used. The crucial question, however, is to explore which parameter is suited best to describe the differences between patients with increased radiosensitivity and healthy individuals. In this study, five patients with severe radiation-induced late effects of at least grade...