TLR2 Is One of the Endothelial Receptors for β2-Glycoprotein I

Volume: 185, Issue: 3, Pages: 1550 - 1557
Published: Aug 1, 2010
Abstract
During the antiphospholipid syndrome, beta2-gpI interacts with phospholipids on endothelial cell (EC) surface to allow the binding of autoantibodies. However, induced-pathogenic intracellular signals suggest that beta2-gpI associates also with a receptor that is still not clearly identified. TLR2 and TLR4 have long been suspected, yet interactions between TLRs and beta2-gpI have never been unequivocally proven. The aim of the study was to...
Paper Details
Title
TLR2 Is One of the Endothelial Receptors for β2-Glycoprotein I
Published Date
Aug 1, 2010
Volume
185
Issue
3
Pages
1550 - 1557
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