E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish

Volume: 12, Issue: 1, Pages: 17 - 17
Published: May 20, 2015
Abstract
Diet-induced hepatic steatosis is highly associated with nonalcoholic fatty liver disease, which is related to the development of metabolic syndrome. While advanced stage nonalcoholic hepatic steatosis and steatohepatitis (NASH) result ultimately in fibrosis and cirrhosis, the molecular basis for lipid droplet formation is poorly understood. Common pathways underlie the pathology of mammalian obesity and the zebrafish diet-induced obesity model...
Paper Details
Title
E2F8 promotes hepatic steatosis through FABP3 expression in diet-induced obesity in zebrafish
Published Date
May 20, 2015
Volume
12
Issue
1
Pages
17 - 17
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