Evaluation of the Sterility, Stability, and Efficacy of Bevacizumab Stored in Multiple-Dose Vials for 6 Months

The aim of this study was to determine the sterility, stability, and efficacy of a commercially available brand of bevacizumab for 6 months of being stored in multidose vials at 4 degrees C.Bevacizumab was aseptically and repeatedly drawn four to five times from new vials into syringes for clinical use within the first month; the remaining bevacizumab was left in the vials and refrigerated at 4 degrees C for 0, 1, 3, and 6 months for research....