Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury.

Volume: 24, Issue: 2, Pages: 99 - 112
Published: Jan 13, 2016
Abstract
Aims: Exposure to irritant gases, such as bromine (Br2), poses an environmental and occupational hazard that results in severe lung and systemic injury. However, the mechanism(s) of Br2 toxicity and the therapeutic responses required to mitigate lung damage are not known. Previously, it was demonstrated that Br2 upregulates the heme degrading enzyme, heme oxygenase-1 (HO-1). Since heme is a major inducer of HO-1, we determined whether an...
Paper Details
Title
Heme Attenuation Ameliorates Irritant Gas Inhalation-Induced Acute Lung Injury.
Published Date
Jan 13, 2016
Volume
24
Issue
2
Pages
99 - 112
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