Evolution of and risk factors for psychological distress in patients with psoriasis: the PSYCHAE study.

Published on Jan 1, 2010in International Journal of Immunopathology and Pharmacology2.209
· DOI :10.1177/039463201002300128
Delia Colombo16
Estimated H-index: 16
A. Caputo2
Estimated H-index: 2
(University of Milan)
+ 4 AuthorsAlberto Giannetti54
Estimated H-index: 54
Psychological distress (PD) is common in patients with psoriasis but little is known about its evolution. The aim of this study is to assess the evolution of PD in psoriasis. For this purpose, 1,505 psoriatic patients, who had been previously enrolled in the PSYCHAE study, an observational multicenter Italian study, were re-evaluated after 6 and 12 months. Minor and major PD were assessed using the General Health Questionnaire (GHQ) and Brief Symptoms Inventory (BSI) questionnaires and coping using Brief COPE questionnaire. Minor PD was present in 46% of patients but halved during the study. Female gender, surface area, topical steroids, methotrexate, self-distraction, venting and behavioral disengagement were risk factors for minor PD; cyclosporine and humor were protective. Major PD was present in 11% of patients and remained stable. Female gender, venting, religion, behavioral disengagement and emotional support were risk factors for major PD; instrumental support was protective. In conclusion, the res...
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