Abrin and Immunoneutralization: A Review
Abstract
Abrin is a type II ribosome-inactivating protein obtained from the mature seeds of a subtropical plant named Abrus precatorius. It is a glycoprotein which arrests protein synthesis in eukaryotes by inactivating ribosomes irreversibly. The heterodimeric protein comprises of the toxic subunit, the A chain which is disulfide bonded to the B chain, a galactose-specific lectin, which helps in binding and trafficking of the toxin in cells. A single...
Paper Details
Title
Abrin and Immunoneutralization: A Review
Published Date
Jan 1, 2014
Journal
Pages
1 - 21
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Notes
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