Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways
Abstract
Primary cilium is an organelle that plays significant roles in a number of cellular functions ranging from cell mechanosensation, proliferation, and differentiation to apoptosis. Autophagy is an evolutionarily conserved cellular function in biology and indispensable for cellular homeostasis. Both cilia and autophagy have been linked to different types of genetic and acquired human diseases. Their interaction has been suggested very recently, but...
Paper Details
Title
Reciprocal regulation of cilia and autophagy via the MTOR and proteasome pathways
Published Date
Apr 23, 2015
Journal
Volume
11
Issue
4
Pages
607 - 616
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