Oncotic pressures opposing filtration across non‐fenestrated rat microvessels
Abstract
We hypothesized that ultrafiltrate crossing the luminal endothelial glycocalyx through infrequent discontinuities (gaps) in the tight junction (TJ) strand of endothelial clefts reduces albumin diffusive flux from tissue into the ‘protected region’ of the cleft on the luminal side of the TJ. Thus, the effective oncotic pressure difference (σ□π) opposing filtration is greater than that measured between lumen and interstitial fluid. To test this we...
Paper Details
Title
Oncotic pressures opposing filtration across non‐fenestrated rat microvessels
Published Date
Jun 1, 2004
Journal
Volume
557
Issue
3
Pages
889 - 907
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