The Cystic Fibrosis Heterozygote Advantage: A Synthesis of Ideas

Volume: 39, Issue: 1/2, Pages: 147 - 147
Published: Jan 1, 1997
Abstract
: It has been proposed that the high frequency of Cystic Fibrosis (CF) is due to a selective advantage in the heterozygous state. This research supports this proposition and attempts a holistic perspective in reviewing the various models proposed. The pathophysiology, molecular and population genetics and the epidemiology are all demonstrated to be key components when evaluating the carrier advantage of CF.Various hypotheses are reviewed and...
Paper Details
Title
The Cystic Fibrosis Heterozygote Advantage: A Synthesis of Ideas
Published Date
Jan 1, 1997
Volume
39
Issue
1/2
Pages
147 - 147
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