Intravenous naftidrofuryl for critical limb ischaemia

Background Peripheral arterial disease affects five per cent of men and women by late middle age. Approximately 25% of those affected will develop critical limb ischaemia (rest pain, ulceration and gangrene) within five years. Naftidrofuryl is a vasoactive drug which may be beneficial in the treatment of critical limb ischaemia. Objectives To determine whether naftidrofuryl, when administered intravenously, is effective in alleviating symptoms...