Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy.
Abstract
Capillary occlusions are characteristic features of the early diabetic retinopathy and are presumed to initiate neovascularization. Activated leukocytes can cause microvascular occlusions and cell damage by release of cytotoxic products. To explore the role of leukocytes in capillary occlusion, nonperfusion, and neovascularization of diabetic retinopathy, a rat model was used, in which a diabetic state was induced by alloxan. Retina flat...
Paper Details
Title
Activated monocytes and granulocytes, capillary nonperfusion, and neovascularization in diabetic retinopathy.
Published Date
Jul 1, 1991
Journal
Volume
139
Issue
1
Pages
81 - 100
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Notes
History