Submicron-scale surface architecture of tricalcium phosphate directs osteogenesis in vitro and in vivo
Volume: 27, Pages: 281 - 297
Published: Apr 15, 2014
Abstract
A current challenge of synthetic bone graft substitute design is to induce bone formation at a similar rate to its biological resorption, matching bone's intrinsic osteoinductivity and capacity for remodelling. We hypothesise that both osteoinduction and resorption can be achieved by altering surface microstructure of beta-tricalcium phosphate (TCP). To test this, two TCP ceramics are engineered with equivalent chemistry and macrostructure but...
Paper Details
Title
Submicron-scale surface architecture of tricalcium phosphate directs osteogenesis in vitro and in vivo
Published Date
Apr 15, 2014
Volume
27
Pages
281 - 297
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