Consequences of the loss of collagen XXIV in bone (922.7)

Fibrillar collagens give integrity and tensile strength to many organs in the body. Collagen XXIV is a non‐traditional collagen in the fibrillar collagen family. To determine what its function might be in bone, collagen XXIV knock out (KO) mice were analyzed. Since femurs of null mice at 3 and 5 months of age were found to be osteoporotic compared to WT mice, our goal was to quantify mRNAs involved in regulation of bone deposition and...