Targeting of Apoptotic Cells Using Functionalized Fe2O3 Nanoparticles
Abstract
Fe2O3 nanoparticles (NPs) have been synthesized and functionalized with SiO2 and -NH2 group, respectively. Conjugation to fluorescently-labeled poly-caspase inhibitor (SR-FLIVO) has been carried out for better cellular uptake studies of apoptosis arising from brain focal cerebral ischemia. Highest conjugation affinity to SR-FLIVO was found to be ca. 80% for Fe2O3-SiO-NH2 functionalized nanoparticles (FNPs). Tracking of SR-FLIVO conjugated...
Paper Details
Title
Targeting of Apoptotic Cells Using Functionalized Fe2O3 Nanoparticles
Published Date
May 26, 2015
Journal
Volume
5
Issue
2
Pages
874 - 884
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