Abstract 3611: Stromal transforming growth factor-beta 1 is crucial for reinforcing the invasive potential of low invasive cancer

Comparative analyses of gene expression profiles between metastatic and non-metastatic cells have revealed that various genes are differentially expressed in association with the metastatic potential of cancer cells. Interactions between tumor cells and their adjacent microenvironment are intimately associated with tumor growth and the development of metastasis. Cancer-associated fibroblasts (CAFs) are a source of various paracrine and autocrine...