Methemoglobin and sulfhemoglobin formation due to benzocaine and lidocaine in macaques

Published: May 13, 1993
Abstract
Benzocaine (BNZ) and lidocaine (LC) are commonly used topical (spray) anesthetics approved for use in humans. BNZ has structural similarities to methemoglobin (MHb) forming drugs that are current candidates for cyanide prophylaxis, while LC has been reported to increase MHb in man. We therefore, compared MHb and sulfhemoglobin (SHb) production in three groups of Macaques (Macaca mulata, Chinese rhesus and Indian rhesus, and Macaca nemistrina,...
Paper Details
Title
Methemoglobin and sulfhemoglobin formation due to benzocaine and lidocaine in macaques
Published Date
May 13, 1993
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