In vitro endocrine modulation within the Hypothalamus-Pituitary-Ovary (HPO) axis : by dioxin like compounds and phytoestrogens
Published: Feb 13, 2015
Abstract
There is a wide range of alternative cellular test systems available, with the majority being derived from relevant organs and tissues that are frequently derived from human origin or embryonic life stages. Nevertheless, in vitro modeling of the full reproductive cycle to predict human reproductive and developmental risk remains a monumental challenge. The aim of this thesis was to study alterations by endocrine disrupting compounds (EDCs) in...
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