Practical utility of insulin-like growth factor II mRNA-binding protein 3, glucose transporter 1, and epithelial membrane antigen for distinguishing malignant mesotheliomas from benign mesothelial proliferations

The differentiation of malignant mesotheliomas and benign mesothelial proliferations is crucial in determining patient care and prognosis. But, this distinction can be extremely difficult, particularly in small biopsies. Recently, insulin‐like growth factor II mRNA ‐binding protein 3 ( IMP3 ) and glucose transporter 1 ( GLUT ‐1) have been reported as specific and sensitive markers in the distinction of mesotheliomas from benign mesothelial...