A Castrated Mouse Model of Erectile Dysfunction

: To establish a mouse model for the study of venoocclusive erectile dysfunction, we investigated erectile function in wild‐type (WT), castrated (CAST), and castrated mice receiving immediate testosterone replacement (TEST). Adult C57BL6 mice (∼30 g) underwent electrical stimulation of the cavernous nerve in vivo (parameters: 16 Hz frequency, 5 ms duration, 4V stimulatory voltage) with intracavernosal pressure (ICP) monitoring. A total of 55...