Montelukast modulates lung CysLT(1) receptor expression and eosinophilic inflammation in asthmatic mice

Volume: 25, Issue: 10, Pages: 1341 - 1346
Published: Oct 1, 2004
Abstract
AIM: To determine the expressions of cysteinyl leukotriene receptors, CysLT1 and CysLT2, in airway eosinophilic inflammation of OVA-induced asthmatic mice and the modulation by montelukast, a CysLT1 receptor antagonist. METHODS: Asthma model was induced by chronic exposure to ovalbumin (OVA) in C57BL/6 mice. The eosinophils in bronchoalveolar lavage (BAL) fluid and lung tissues were counted, IL-5 level in BAL fluid was measured, and CysLT1...
Paper Details
Title
Montelukast modulates lung CysLT(1) receptor expression and eosinophilic inflammation in asthmatic mice
Published Date
Oct 1, 2004
Volume
25
Issue
10
Pages
1341 - 1346
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