IL-18 is highly expressed in inflammatory infiltrates of submandibular glands in patients with immunoglobulin G4–related disease
Abstract
Immunoglobulin (Ig) G4-related disease (IgG4-RD) is a new disease entity characterized by high serum IgG4 concentrations, infiltration of IgG4-positive plasmacytes, and fibrosis of various organs. Several groups have reported that IgG4-RD is a unique inflammatory disorder characterized by an immune reaction predominantly mediated by T helper (Th) 2 and regulatory T cells. Meanwhile, recent studies have demonstrated that interleukin (IL) 18 has a...
Paper Details
Title
IL-18 is highly expressed in inflammatory infiltrates of submandibular glands in patients with immunoglobulin G4–related disease
Published Date
Dec 1, 2015
Journal
Volume
46
Issue
12
Pages
1850 - 1858
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Notes
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