The synthesis of coumarin derivatives using choline chloride/zinc chloride as a deep eutectic solvent

In this work, choline chloride/zinc chloride was employed as a deep eutectic solvent (DES) in the green synthesis of coumarin derivatives using Knoevenagel condensation. Coumarins are important organic structures with useful application in various fields. The procedure consisted of the reaction between salicylaldehyde derivatives and active methylene compounds (dimethyl malonate, ethyl cyano acetate and ethyl 3-oxo-3-phenylpropanoate) to produce...