The natural history of community-acquired common colds symptoms assessed over 4-years

Background: The common cold is the most frequently experienced infection among humans, but limited data exist to characterize the onset, duration, severity and intersection of symptoms in community-acquired colds. A more complete understanding of the symptom frequency and burden in naturally occurring colds is needed. Methodology: We characterized common cold symptoms from 226 cold episodes experienced by 104 male or female subjects. Subjects...