Geometric guidance of integrin mediated traction stress during stem cell differentiation
Abstract
Cells sense and transduce the chemical and mechanical properties of their microenvironment through cell surface integrin receptors. Traction stress exerted by cells on the extracellular matrix mediates focal adhesion stabilization and regulation of the cytoskeleton for directing biological activity. Understanding how stem cells integrate biomaterials properties through focal adhesions during differentiation is important for the design of soft...
Paper Details
Title
Geometric guidance of integrin mediated traction stress during stem cell differentiation
Published Date
Nov 1, 2015
Journal
Volume
69
Pages
174 - 183
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