Accuracy of Pupil Assessment for the Detection of Glaucoma

Objective To assess the accuracy of using pupillary light reflex (PLR) in detecting glaucoma. Clinical Relevance Glaucoma is a specific disease of the optic nerve and is often more severe in 1 eye. When large enough, this asymmetry in disease severity can cause a relative afferent pupillary defect (RAPD). Better detection of RAPDs may be one way to identify persons with glaucoma. Methods We searched Medline and Embase through June 2012 and...