Lamina Cribrosa Depth is Associated with Cup-to-disc Ratio in Eyes with Large Optic Disc Cupping and Cup-to-disc Ratio Asymmetry

Published on Jun 11, 2015in Investigative Ophthalmology & Visual Science4.799
Kyoung In Jung13
Estimated H-index: 13
(Catholic University of Korea),
Chan-Kee Park1
Estimated H-index: 1
(Catholic University of Korea)
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Cited By1
#1Thanadet Chuangsuwanich (NUS: National University of Singapore)H-Index: 2
#2K. Erik Birgersson (NUS: National University of Singapore)H-Index: 1
Last. Michael J A Girard (NUS: National University of Singapore)H-Index: 35
view all 6 authors...
Purpose: To identify and rank the lamina cribrosa (LC) morphologic factors that influence LC microcapillary hemodynamics and oxygen concentrations using computational fluid dynamics (CFD). Methods: We generated 12,000 'artificial' LC microcapillary networks and predicted blood flow velocities and oxygen concentrations within the microcapillaries using CFD. Across models, we varied the average pore size of the LC (5500 ± 2400 μm2), the microcapillary arrangement (radial, isotropic, or circumferen...
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