The Open Circulation & Vascular Journal
Papers 32
1 page of 4 pages (32 results)
#1Yanchun HuH-Index: 1
#2Shenju SongH-Index: 1
Last. Yanxia HuH-Index: 1
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To understand the hemodynamics of the microcirculation, we compared the resistance of vessels that either had an enlarged cross-sectional area in the midsection (denoted vessel 1) or had a uniform diameter (denoted vessel 2). The length of the two vessels and the pressure difference between the ends were equal. The two vessels were filled with water, and the volume of water flowing through the two vessels per second was measured. The volume of water flowing through vessel 1 was 4.05 ml/sec, and ...
1 CitationsSource
Aorta is the largest artery in the body. Anatomically, it is traditionally divided into the ascending, the aortic arch, the descending, the thoracic and the abdominal aorta. Collagen is one of the most important components of the aortic wall. Its concentration and its total amount play a significant role in the aortas' function and mechanical properties, such as tensile strength and stiffness. The two main types of collagen found in the aorta are types I and III and they account for 80-90% of th...
26 CitationsSource
Renal artery aneurysms are rare, but their reported incidence has increased as a result of the widespread use of imaging techniques. Most aneurysms are asymptomatic and discovered incidentally; however, they can present with refractory hypertension, pain and hematuria. We report the case of a 42 year old normotensive woman who presented with acute lower back pain with unremarkable lumbar x rays, in the setting of acute anemia with hypotension, leading to a high suspicion for internal bleeding. C...
#1Pooja Bhatt (OU: Ohio University)H-Index: 7
#2Christopher J. Lewis (OU: Ohio University)H-Index: 7
Last. Ramiro Malgor (Heritage College of Osteopathic Medicine)H-Index: 13
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Objective: Wnt5a is a secreted glycoprotein highly present in atherosclerotic lesions. Uptake of oxidized-low density lipoprotein (ox-LDL) by monocytes/macrophages plays a critical role in atherosclerosis. The objective of this study was to determine if Wnt5a mRNA expression correlates with the severity of atherosclerotic lesions, and if, ox-LDL can induce Wnt5a mRNA in macrophages. Methods: Wnt5a mRNA in tissue sections from carotid arteries of patients undergoing endarterectomy was quantified ...
25 CitationsSource
The discovery of postnatal vasculogenesis and of the important roles played by bone marrow-derived Endothelial Progenitor Cells was a landmark in vascular biology that forever has changed the concept of neovascularization. Diabetes associated vascular complications involve distinct modifications in neovascular formation, which is reduced in cardiovascular disease and increased in diabetic retinopathy, defining the diabetic paradox. The vasculogenic process seems to play a central dual role in th...
1 CitationsSource
Lymphatic and venous systems work together to drain interstitial fluid and blood respectively. Data on lym- phatic function in chronic venous insufficiency and in chronic venous ulcerations are discordant. Modification of lymphatic function in acute venous thrombosis have been never described. The aim of this study is to report the modifications of the function of the lymphatic system in acute venous thrombosis, chronic venous ulceration and post-thrombotic syndrome. Material and Methods: Patien...
2 CitationsSource
Shear stress, the frictional drag on the endothelium from blood flow, is a major determinant of vascular physi- ology and pathology. Due to the pulsatile nature of blood flow, blood vessels are subjected to significant variations in me- chanical forces. Endothelial cells situated at the interface between blood and the vessel wall play a crucial role in detecting and responding to the mechanical forces generated by shear stress. Multiple sensing mechanisms are used by endothelial cells to detect ...
14 CitationsSource
Altered endothelial activity is enumerated amongst the leading causes of graft dysfunction following coronary artery bypass surgery and may account for differences in patency between arterial and venous grafts. This study investigates whether differences exist between basal endothelial functions of saphenous vein (SV) and internal mammary arteries (IMA) and explores the putative involvements of reactive oxygen species in this phenomenon. Basal relaxations were greater in IMA than SV. Specific in...
1 CitationsSource
Pressure ulcers, also called decubitus ulcers, are a common challenge of humanity. They are wounds initiated by pressure on the skin that blocks circulation causing the skin and underlying tissues to die. Without care, pressure ulcers continue to grow in diameter and depth and are exceptionally difficult to heal. They have probably always existed, and are present on Egyptian mummies. Pressure ulcers are a serious health issue, very painful, a significant physiological challenge, can shorten the ...
9 CitationsSource
Top fields of study
Diabetes mellitus