Advances in Medical Sciences
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951
Papers 994
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#1Fatemeh Fardi Golyan (MUMS: Mashhad University of Medical Sciences)H-Index: 3
#2Mohammad Mahdi Forghanifard (IAU: Islamic Azad University)H-Index: 17
Abstract Purpose Esophageal squamous cell carcinoma (ESCC) is categorized among ten common aggressive malignancies, with a higher incidence and mortality rates in the developing than in developed countries. The inositol polyphosphate 5-phosphatase (INPP5A), as an intracellular-calcium mobilizer and modifier enzyme, facilitates cell responses to various stimuli. Epithelial-mesenchymal transition (EMT), a transformation procedure, has a vital role in cancer progression and metastasis when epitheli...
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#1Leanne Brechtel (USC: University of South Carolina)H-Index: 4
#2Nicolas Poupore (USC: University of South Carolina)H-Index: 3
Last. Thomas I. Nathaniel (USC: University of South Carolina)H-Index: 14
view all 8 authors...
Abstract Purpose The relationship between the telestroke technology and clinical risk factors in a dysplipidemic ischemic stroke population and neurologic outcomes is not fully understood. This issue was investigated in this study. Patients and methods We analyzed retrospective data collected from a regional stroke registry to identify demographic and clinical risk factors in patients with improving (NIHSS ​≤ ​7) or worsening (NIHSS ​> ​7) neurologic outcome in dyslipidemic ischemic stroke popul...
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#1L. Boglione (University of Eastern Piedmont)H-Index: 3
#2Carlo OlivieriH-Index: 9
Last. Silvio BorréH-Index: 2
view all 9 authors...
ABSTRACT Purpose Severe coronavirus disease 2019 (COVID-19) is strongly related to interstitial pneumonia with frequent development of acute respiratory distress syndrome (ARDS). The role of corticosteroids (CS) treatment in these patients is still controversial. Some studies evidenced a possible role of an early short-term course of CS treatment in the treatment of severe pneumonia. Patients and methods This is a single-center, retrospective study considering the patients with confirmed COVID-1...
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#1Szymon Skoczyński (Medical University of Silesia)H-Index: 7
#2Maciej Ogonowski (Medical University of Silesia)H-Index: 1
Last. Adam Barczyk (Medical University of Silesia)H-Index: 13
view all 14 authors...
PURPOSE Flexible bronchoscopy (FB) causes airway narrowing and may cause respiratory failure (RF). Noninvasive mechanical ventilation (NIV) is used to treat RF. Until recently, little was known about noninvasive mechanical ventilation assisted flexible bronchoscopy (NIV-FB) risk and complications. MATERIALS AND METHODS A retrospective analysis of NIV-FB performed in 20 consecutive months (July 1, 2018-February 29, 2020) was performed. Indications for: FB and NIV, as well as impact of comorbiditi...
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#1Radoslaw Charkiewicz (UMB: Medical University of Białystok)H-Index: 9
#2Jacek Niklinski (UMB: Medical University of Białystok)H-Index: 25
Last. Joanna Reszeć (UMB: Medical University of Białystok)H-Index: 10
view all 13 authors...
Abstract Purpose We analyzed the SARS-CoV-2 genome using our integrated genome analysis system and present the concept of a comprehensive approach to monitoring and surveillance of emerging variants. Material/methods A total of 69 SARS-CoV-2 positive samples (with Ct value ​≤ ​28) were tested. Samples included in this study were selected from 7 areas of eastern Poland. All samples were sequenced on an Illumina MiSeq platform using a 300-cycle MiSeq Reagent Kit v2. BWA was used for reads mapping ...
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#1Angelika Edyta Charkiewicz (UMB: Medical University of Białystok)H-Index: 5
#2Marzena Garley (UMB: Medical University of Białystok)H-Index: 9
Last. Wioleta J. Omeljaniuk (UMB: Medical University of Białystok)H-Index: 3
view all 7 authors...
Abstract Purpose Normal endothelial function is important for the homeostasis of the cardiovascular (CV) system. The aim of the present study was to determine the profile of key parameters of endothelial dysfunction in middle-aged men that play a significant role in the functioning of endothelial vessels, which seems to be crucial for the early diagnosis of cardiovascular disorders. Materials and methods The study included 53 men, 20 with hypertension (HTN), 18 with HTN and related diseases, 15 ...
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#1Monika Szeliga (PAN: Polish Academy of Sciences)H-Index: 13
#2Jan Albrecht (PAN: Polish Academy of Sciences)H-Index: 36
Abstract Nitric oxide (NO) and polyamines: putrescine, spermidine and spermine, are key arginine metabolites in mammalian tissues that play critical roles i.a. in regulation of vascular tone (NO), and cell cycle regulation (polyamines). In the brain, both classes of molecules additionally have neuromodulatory and neuroprotective potential, and NO also a neurotoxic potential. Here we review evidence that brain tumors use the NO- and polyamine-synthesizing machineries to the benefit of their diffe...
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#1Tomasz Lyson (UMB: Medical University of Białystok)H-Index: 10
#2Joanna Kisluk (UMB: Medical University of Białystok)H-Index: 5
Last. Ricardo L. Carrau (The Ohio State University Wexner Medical Center)H-Index: 68
view all 12 authors...
Abstract Transnasal endoscopic skull base surgery (eSBS) has been adopted in recent years, in great part to replace the extended procedures required by external approaches. Though sometimes perceived as “minimally invasive”, eSBS still necessitates extensive manipulations within the nose/paranasal sinuses. Furthermore, exposure of susceptible cerebral structures to light and heat emanated by the telescope should be considered to comprehensively evaluate the safety of the method. While the number...
1 CitationsSource
#1Aleksandra Majchrzak-Celińska (Poznan University of Medical Sciences)H-Index: 9
#2Małgorzata Zielińska-Przyjemska (Poznan University of Medical Sciences)H-Index: 9
Last. Violetta Krajka-Kuźniak (Poznan University of Medical Sciences)H-Index: 16
view all 9 authors...
4 CitationsSource
#1Isela C. Valera (FSU: Florida State University)H-Index: 1
#2Amanda L. Wacker (FSU: Florida State University)H-Index: 1
Last. Michelle S. Parvatiyar (FSU: Florida State University)H-Index: 14
view all 7 authors...
Abstract The dystrophin-glycoprotein complex (DGC), situated at the sarcolemma dynamically remodels during cardiac disease. This review examines DGC remodeling as a common denominator in diseases affecting heart function and health. Dystrophin and the DGC serve as broad cytoskeletal integrators that are critical for maintaining stability of muscle membranes. The presence of pathogenic variants in genes encoding proteins of the DGC can cause absence of the protein and/or alterations in other comp...
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