Iranian Journal of Pharmaceutical Research
Papers 2639
1 page of 264 pages (2,639 results)
#1Mohammadreza Sattari (Tabriz University of Medical Sciences)H-Index: 10
#2Ali Ostadi (Tabriz University of Medical Sciences)H-Index: 4
Last. Armin Salek Maghsoudi (Tehran University of Medical Sciences)H-Index: 5
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Background Changes in plasma concentration of taurine during hospitalization of acetaminophen poisoned patients has not been studied. Objective Hepatotoxicity is a common consequence of acetaminophen overdose that may lead to acute liver failure. Numerous biomarkers for drug-induced liver injury have been explored. All biomarkers are usually obtainable 48 hours following acetaminophen overdose. We have already introduced taurine as a non-specific early biomarker of acetaminophen overdose. The ai...
#1Hassan Askari (Shiraz University of Medical Sciences)H-Index: 9
#2Noora Enayati (Shahid Beheshti University)
Last. Amirhesam Alirezaei (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 6
view all 5 authors...
Several studies have tried to find an efficient agent to prevent or reverse gentamicin (Gm) induced acute kidney injury (AKI). In this study, we assessed the potential renal protective effects of Descurainia sophia (L.) Webb ex Prantl against Gm-induced nephrotoxicity in rats. Thirty-five male Wistar rats were categorized in five groups (n = 7 per group). Control group was treated with normal saline. In four experimental groups, the rats were initially treated with normal saline (A), 800 (B), 16...
#1Anoosheh Maruzi (U of S: University of Saskatchewan)
#2Sara Sabbaghian-Tousi (MUMS: Mashhad University of Medical Sciences)
Last. Sepideh Elyasi (MUMS: Mashhad University of Medical Sciences)H-Index: 9
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The Mashhad drug and poison information center (MDPIC) was officially established in 2000 to provide up-to-date information on medications. The objective of this study is to provide an epidemiologic profile of drug inquiry and poisoning-related phone calls to MDPIC from 2007 to 2017. This article is a descriptive retrospective study in which all inquiries about drugs and poisoning cases received by MDPIC, from 1st January 2007 to 31st December 2017, were retrieved from its database for analysis....
#1L. Eslamian (Tehran University of Medical Sciences)H-Index: 9
Last. Mahnaz Ahmadi (Shahid Beheshti University of Medical Sciences and Health Services)H-Index: 1
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#1Elham Salehi (IAU: Islamic Azad University)
#2Mohammad Mashayekh (IAU: Islamic Azad University)
Last. Afrah Sepehr (IUMS: Iran University of Medical Sciences)
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Previous studies have shown that alcohol abuse can cause serious liver damage and cirrhosis. The main pathway for these types of hepatocellular cell neurodegeneration is mitochondrial dysfunction, which causes lipid peroxidation and dysfunction of the glutathione ring and the defect of antioxidant enzymes in alcoholic hepatic cells. Alcohol can also initiate malicious inflammatory pathways and trigger the initiation and activation of intestinal and extrinsic apoptosis pathways in hepatocellular ...
#1Parvin Jahanbani (Kermanshah University of Medical Sciences)
#2Sajjad Nasseri (Kermanshah University of Medical Sciences)H-Index: 1
Last. Mahdi Mojarrab (Kermanshah University of Medical Sciences)H-Index: 10
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Antioxidant activity of five different extracts (petroleum ether, dichloromethane, ethyl acetate, ethanol and ethanol-water) of Artemisia aucheri aerial parts was investigated by three various methods: ferrous ion chelating (FIC) assay, 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging method and β-carotene bleaching (BCB) test. Total phenolic contents (TPC) were measured by Folin–Ciocalteu method. The hydroethanolic extract exhibited the stronger inhibitory activity in BCB and FIC assays ...
#1Mohammad Ali Behnam (SUTECH: Shiraz University of Technology)H-Index: 3
#2Farzin Emami (SUTECH: Shiraz University of Technology)H-Index: 11
Last. Zahra Sobhani (Shiraz University of Medical Sciences)H-Index: 12
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A new technique for cancer therapy is Photo Thermal Therapy (PTT). In the PTT technique, photon energy is converted into heat via various operations to destroy malignant tumors. Carbon nanotubes (CNTs) have good optical absorption in the near-infrared (NIR) spectrum and could transform optical energy into heat to induce hyperthermia in the PTT method. In this study, CNTs were firstly oxidized (O-CNT) and then decorated with silver nanoparticles (Ag NPs). Polyethylene glycol (PEG) was utilized fo...
#1Sara Soltanian (SBUK: Shahid Bahonar University of Kerman)H-Index: 7
#2Mahboubeh Sheikhbahaei (SBUK: Shahid Bahonar University of Kerman)H-Index: 2
Non-small cell lung cancer (NSCLC) is the most common type of lung cancer. Chemotherapy-induced adverse effects and resistance of NSCLC to conventional drugs reduce the efficacy of current therapies. Tumors contain a small population of cancer stem cells (CSCs) that play a critical role in tumor initiation, maintenance, and drug resistance that finally lead to cancer recurrence. Therefore, CSC-targeting therapies can offer the best hope for developing curative cancer therapies. Vitamins have a h...
#1Hadi Kalantar (Ahvaz Jundishapur University of Medical Sciences)H-Index: 6
#2Mohsen Rashidi (Mazandaran University of Medical Sciences)H-Index: 5
Last. Sayed Mostafa Hosseini (BMSU: Baqiyatallah University of Medical Sciences)H-Index: 4
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Epigenetic mechanisms are the most important factors contributing to both the development and metastasis of cancer cells. We aimed to scrutinize the role of epigenetic alternations of genes involved in cancer metastasis, including CD44v6 (metastasis indicator) and Nm23-H1 (a novel tumor suppressor), in the A549 lung cancer cell line. The A549 cells were cultured in the DMEM medium. Valproic acid (VPA) was used as a histone deacetylase inhibitor. Caspase-3 activity was assessed by adding DEVD-pNA...
#1Hamidreza Taghvaye-Masoumi (University of Gilan)H-Index: 2
#2Molouk Hadjibabaie (Tehran University of Medical Sciences)H-Index: 16
Last. Ardeshir Ghavamzadeh (Tehran University of Medical Sciences)H-Index: 28
view all 6 authors...
There are conflicting data regarding the association between plasma concentration of voriconazole (VCZ) and both efficacy and safety. This study investigates the association of VCZ trough plasma level with clinical efficacy and hepatotoxicity in the Iranian population suffering hematological malignancies. This cross-sectional study was performed on adult Iranian patients (age ≥ 18 years) with hematological malignancies undergoing treatment with oral or intravenous VCZ for proven or probable inva...
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Traditional medicine