Chinese Journal of Ocular Fundus Diseases
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3147
Papers 3130
1 page of 313 pages (3,130 results)
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#1Yajun Gong (SYSU: Sun Yat-sen University)H-Index: 2
#2Kunbei Lai (SYSU: Sun Yat-sen University)H-Index: 4
Last. Chenjin Jin (SYSU: Sun Yat-sen University)H-Index: 9
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Choroidal neovascularization is the leading causes of central vision loss in wet age-related macular degeneration (wAMD) patients. Smoking not only aggravates the incidence and severity of the choroidal neovascularization of wAMD, but also affects the clinical treatment, making the prognosis worse. Nicotine, as an important harmful substance in tobacco, is an easily addictive and highly toxic alkaloid. Animal experiments and clinical studies have confirmed that nicotine can aggravate wAMD by med...
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#1Manhui Zhu (Soochow University (Suzhou))H-Index: 6
#2Yuanyuan Tu (Soochow University (Suzhou))H-Index: 4
Last. E Song (Soochow University (Suzhou))
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Objective To observe the protective effect of Zhicao Tea Mixture on Muller cells and the expression of inflammatory factors in mice with diabetic retinopathy. Methods Seventy-five C57BL/6J mice were randomly divided into the normal control group, diabetes mellitus (DM) group, low concentrations group, medium concentrations group and high concentrations group, with 16 mice in each group. The diabetes model of mice in all groups except the normal control group were established by intraperitoneal i...
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#1Mingming Sun (Chinese PLA General Hospital)H-Index: 3
#2Huanfen Zhou (Chinese PLA General Hospital)H-Index: 7
Last. Quangang Xu (Chinese PLA General Hospital)H-Index: 7
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Objective To investigate the clinical, laboratory and imaging evaluation, treatment and prognosis of patients with idiopathic hypertrophic pachymeningitis (IHP) with ophthalmic manifestations as the first symptom. Methods A retrospective case analysis. Eight patients displaying symptoms of IHP were recruited from the Neuro-ophthalmology Department in the First Medical Center of Chinese PLA General Hospital from January 2016 to April 2019 were inculed in this study. There were 6 males and 2 femal...
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#1Bibo Fu (CSU: Central South University)
#2Xiaoling Chen (CSU: Central South University)
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Objective To observe the macular vascular density and the area of foveal avascular zone(FAZ) in the follow eyes of monocular retinal vein occlusion (RVO) patients. Methods Retrospective case-control study. From May to November 2018, 78 follow eyes of 78 monocular RVO patients who were clinically diagnosed in Changsha Aier Eye Hospital were included in the study. Among them, 44 were male and 34 were female. The average age was 53.17±10.12 years. There were 42 patients with central retinal vein oc...
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#1Yifan Liu (WHU: Wuhan University)
#2Yin Shen (WHU: Wuhan University)H-Index: 5
Objective To investigate the protective effects of different concentrations of chloroquine on RGC in n-methyl-d-aspartate (NMDA) injured mice and its possible mechanisms. Methods Fifty-four healthy male C57/BL6 mice were randomly divided into three groups, 18 in each group. The mice in low-dose chloroquine group were intraperitoneally injected with chloroquine solution at a dose of 10 mg/kg daily. Mice in high-dose chloroquine group were intraperitoneally injected with chloroquine solution at a ...
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#1Honglu Song (Chinese PLA General Hospital)H-Index: 5
#2Mo Yang (Chinese PLA General Hospital)H-Index: 6
Last. Shihui Wei (Chinese PLA General Hospital)H-Index: 15
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Objective To observe the clinical, radiographic features and prognosis of aquaporin-4 antibody positive pediatric optic neuritis (AQP4-PON). Methods A retrospective case series. Twenty-three eyes of 14 children with AQP4-PON who were clinically confirmed in the Department of Ophthalmology of the First Medical Center of the Chinese PLA General Hospital from January 2015 to December 2018 were included in the study. All patients underwent BCVA, fundus color photography, and magnetic resonance imagi...
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#1Qing Xiao (ZJU: Zhejiang University)
#2Chuanbin Sun (ZJU: Zhejiang University)
Last. Huanfen Zhou (Chinese PLA General Hospital)H-Index: 7
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Objective To observe the clinical features and visual prognostic factors of ethambutol-induced optic neuropathy (EON). Methods A cohort study. Twenty-four inpatients (46 eyes) identified as EON in Neuro-Ophthalmology Department of Chinese PLA General Hospital from January 2014 to December 2017 were enrolled, including 14 males (26 eyes) and 10 females (20 eyes) with a ratio of 1.4/1 male/female. The average age was 42.79±15.12 years and the average weight was 62.46±12.31 kg. The average time dur...
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#1Xueting Yu (WMU: Wenzhou Medical College)H-Index: 2
#2Jiwei Tao (WMU: Wenzhou Medical College)H-Index: 5
Last. Lijun Shen (WMU: Wenzhou Medical College)H-Index: 5
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Dissociated optic nerve fiber layer (DONFL) appearance is consists of numerous arcuate dark striae within the posterior pole in the direction of the optic nerve fibers. And on the cross-sectional image, DONFL was correspond to inner retinal dimples. It mainly occurs after the internal limiting membrane (ILM) peeling due to the direct damage on the local retina and the broad tractional effect on the posterior retina during membrane peeling. DONFL appearance is considered to be a spontaneous and d...
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Objective To evaluate the efficacy and safety of reduced-dose intravitreal ganciclovir for the treatment of acquired immunodeficiency syndrome (AIDS) patients with cytomegalovirus retinitis (CMVR). Methods A prospective observational cohort study observed 15 AIDS patients (28 eyes) who suffered from CMVR onset between January 2016 and December 2018 at Nanning Aier Eye Hospital. Among this 28 eyes, BCVA of 6 eyes (21.4%) were between moving hand to counting finger, 15 eyes (53.6%) were between 0....
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#1Shumin Zhou (Tianjin Medical University)H-Index: 6
#2Fanqiang Kong (Tianjin Medical University)H-Index: 6
Last. Song Chen (Tianjin Medical University)H-Index: 6
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Objective To preliminarily investigate the mechanism of MMP-9 blocking CD73 detachment from RPE cells surface and preventing and treating experimental autoimmune pigment membranitis(EAU). Methods RPE cells isolated from wild-type C57BL/6 and CD73 gene knockout (CD73-/-) mice were cultured in vitro, and treated with lipopolysaccharide and TNF-α to induce CD73 detachment from RPE surface. According to whether MMP-9 inhibitor CTK8G1150 was added at the same time (the final concentration was 5.0 mol...
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Top fields of study
Ophthalmology
Surgery
Fundus (eye)
Retina
Visual acuity
Retinal
Medicine