Journal of Peking University. Health sciences
Papers
2910
Papers 3138
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Newest
#1G H Wang (Anhui Medical University)
#2T Zuo (Anhui Medical University)
Last. Z C Zuo (Anhui Medical University)
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OBJECTIVE To investigate the role of rebamipide in the treatment of acute gout arthritis rats induced by monosodium urate (MSU) crystal. METHODS Forty-two male rats were randomly divided into three groups (n=14). Group A was treated with oral rebamipide, group B with oral colchicine, and group C with oral placebo. The rats were monitored for the induction of arthritis with clinical manifestations and pathological changes, and the levels of interleukin (IL)-1β、IL-6、IL-10, and tumor necrosis facto...
#1Lixin Wang (Capital Medical University)H-Index: 1
#2Xitong Xu (PKU: Peking University)H-Index: 9
Last. Siye Wei (PKU: Peking University)H-Index: 15
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OBJECTIVE To develop dexamethasone plus minocycline-loaded liposomes (Dex/Mino liposomes) and apply them to improve bioinert polyetheretherketone (PEEK) surface, which could prevent post-operative bacterial contamination, enhance ossification for physiologic osseointegration, and finally reduce implant failure rates. METHODS Dex/Mino liposomes were covalently grafted onto the PEEK surface using polydopamine (pDA) coating as a medium. Confocal laser scanning microscopy was used to confirm the bin...
#1Qingjie Wang (PKU: Peking University)H-Index: 9
#2Wei Zhang (PKU: Peking University)H-Index: 13
Last. K X Xu (PKU: Peking University)H-Index: 4
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OBJECTIVE To evaluate the effects of sacral neuromodulation (SNM) on detrusor underactivity (DUA). METHODS From December 2019 to April 2020, 6 patients with DUA who had been treated with SNM were assessed retrospectively. The average age was 58 years (46-65 years), with 3 males and 3 females. All the patients were diagnosed with DUA by urodynamics examination. Obstruction of bladder outlet was excluded through the cystoscopy. No patient had the history of neurological disease. All the patients w...
#1Z H Sun (PKU: Peking University)
#2Xin Huang (PKU: Peking University)H-Index: 14
Last. Lanqing Ma (PKU: Peking University)H-Index: 16
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OBJECTIVE To summarize the clinicoradiological characteristics of clinical T1 renal cell carcinoma patients and to investigate the risk factors of renal sinus invasion in cT1 renal cell carcinoma patients undergoing nephrectomy. METHODS A retrospective study was conducted in cT1 renal cell carcinoma patients from January 2016 to August 2019 in Department of Urology, Peking University Third Hospital, who underwent partial or radical nephrectomy by analyzing clinicopathological and radiological da...
#1Linzhi Liu (PKU: Peking University)H-Index: 1
#2Yu Qin (PKU: Peking University)H-Index: 14
Last. Lanqing Ma (PKU: Peking University)H-Index: 16
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Objective null To explore the surgical strategy and experience of reoperation for pheochromocytoma and paraganglioma which is very challenging. null Methods null The clinical data of 7 patients with pheochromocytoma and paraganglioma who underwent reoperation in Department of Urology, Peking University Third Hospital from August 2016 to February 2021 were analyzed retrospectively. There were 4 males and 3 females, with an average age of (44.1±11.5) years (28-60 years), 6 cases on the right side ...
#1Xiao-qiu Dai (PKU: Peking University)
#2M N Zuo (PKU: Peking University)
Last. T Xu (PKU: Peking University)H-Index: 5
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OBJECTIVE To compare the short-term effects and long-term outcomes of incisional procedure and dilatation procedure to manage diverticular neck in percutaneous nephrolithotomy for diverticular stones. METHODS Clinical data of 61 patients with diverticular stones who underwent percutaneous nephrolithotomy from June 2009 to January 2019 were retrospectively collected and analyzed, which was as follous: (1) basic information: age, gender, body mass index (BMI), American Society of Anesthesiology (A...
#1Q Du (PRC: China Medical University (PRC))
#2Kai Hong (PKU: Peking University)H-Index: 4
Last. B C Pan (PRC: China Medical University (PRC))
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Objective null To investigate the value of clinical application of simultaneous amplification and testing of RNA (SAT-RNA) for detecting Chlamydia trachomatis (CT) and Ureaplasma urealyticum (UU) by comparing with the polymerase chain reaction testing of DNA (PCR-DNA) method. null Methods null Specimens from both urethra swab and the first avoid urine which should be at least one hour after the previous urination were collected from 163 men who were scheduled for in vitro fertilization and embry...
#1Hongqiao Gao (PKU: Peking University)H-Index: 7
#2Hong Meng (PKU: Peking University)H-Index: 44
Last. Wenzhu Li (PKU: Peking University)H-Index: 2
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OBJECTIVE Calprotectin, the heterdimer of S100A8 and S100A9, is the major cytoplasmic protein of neutrophils, which is also expressed or induced in gingival epithelial cells, activated mononuclear macrophages and vascular endothelial cells. Calprotectin is intimately associated with the initiation and progression of periodontitis, but the in vivo expression patterns of calprotectin in healthy and inflamed periodontal tissue are not fully understood. To observe the expression, distribution and ce...
#1Xuefei Ma (PKU: Peking University)H-Index: 5
#2X W Zhang (PKU: Peking University)H-Index: 3
Last. Li Yq (PKU: Peking University)H-Index: 3
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OBJECTIVE To explore the significance of lymphocytes in systemic sclerosis (SSc), by detecting the levels of T lymphocytes, B lymphocytes and natural killer (NK) cells, and analyzing the correlation between the lymphocytes and clinical laboratory indexes. METHODS The numbers and proportion of T, CD4+T, CD8+T, B, and NK cells were detected by flow cytometry in peripheral blood of 32 SSc patients who had taken immunosuppressive drugs and 30 healthy controls (HC). The comparison of the lymphocyte s...
#1Xinguang Wang (PKU: Peking University)H-Index: 1
#2Xiao Geng (PKU: Peking University)H-Index: 1
Last. Hong Tian (PKU: Peking University)
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OBJECTIVE To explore the differences of alignment and operative time between portable accelerometer-based navigation device (PAD) and computer assisted surgery (CAS) in total knee arthroplasty (TKA). METHODS Data of patients using iASSIST (a kind of PAD) and OrthoPilot (a kind of CAS) for TKA in Peking University Third Hospital from December 2017 to December 2019 were retrospectively collected. The differences of preoperative general data, preoperative alignment, operative time and postoperative...
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