Journal of the Brazilian Chemical Society
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#1Clebson J. MacrinoH-Index: 3
#2Elias M. da Silva (UFES: Universidade Federal do Espírito Santo)H-Index: 2
Last. Wanderson RomãoH-Index: 28
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#1Muhammad Masood Ahmed (BZU: Bahauddin Zakariya University)H-Index: 1
#1Muhammad Mahboob Ahmed (BZU: Bahauddin Zakariya University)H-Index: 2
Last. Muhammad SajidH-Index: 51
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#1Simone Nascimento (Agilent Technologies)H-Index: 1
Last. Quezia B. CassH-Index: 35
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#1Min-Fu N. Huang (UFPB: Federal University of Paraíba)
#1Min-Fu HuangH-Index: 1
Last. José Maria Barbosa-FilhoH-Index: 53
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This study describes a virtual screening performed for two series of selenides (28 compounds), derived from N-phenylacetamides chlorides and 7-chloro-quinoline, to determine their potential for leishmanicidal activity against Leishmania amazonensis and Leishmania donovani. Seven compounds were predicted as potential leishmanicides; therefore, they were synthesized from elemental selenium, as a precursor for the production of NaHSe, and subsequent reactions with 4,7-dichloro-quinoline and N-pheny...
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