M. Sarasija
Osmania University
Proton NMRNuclear chemistryMedicinal chemistryCatalysisCarbon-13 NMROrganic chemistryChemistryIn vitroCombinatorial chemistryMoietyBacillus subtilisPyrazoleThiazoleCycloadditionAntimycobacterialAntibacterial activity1,2,3-TriazoleArylAntimicrobialClick chemistry
36Publications
5H-index
78Citations
Publications 36
Newest
#1Dongamanti Ashok (Osmania University)H-Index: 9
#2M. Ram Reddy (Osmania University)H-Index: 2
Last. M. SarasijaH-Index: 5
view all 6 authors...
A series of new 1,2,3-triazole derivatives were designed and synthesised through Cu(I) catalysed 1,3-dipolar cycloaddition of alkynes and organic azides namely click reaction, under both conventional and microwave irradiation methods. Higher yields were achieved in lesser time under microwave irradiation method by using CuI as the catalyst. Herein, the two triazole moieties are linked through the O-alkoxy oxime linkage. All the synthesised molecular structures are elucidated by 1H-NMR, 13C-NMR, ...
2 CitationsSource
#1Sridhar Pervaram (Osmania University)H-Index: 2
#2Dongamanti Ashok (Osmania University)H-Index: 9
Last. Arram GaneshH-Index: 6
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Abstract A simple, efficient, eco-friendly and a green synthetic method has been developed for the synthesis of polysubstitutedpyrrolidinone derivatives via one-pot multi component reaction of aromatic aldehydes, aromatic amines with dimethyl but-2-ynedioate by using inexpensive non-toxic ionic liquid [bmim]BF4 under PEG-400 medium. The present methodology offers more environmental acceptability, higher yields with very shorter reaction time and recyclability of the ionic liquid.
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#1Ravinder Dharavath (Osmania University)H-Index: 2
#2M. SarasijaH-Index: 5
Last. Dongamanti Ashok (Osmania University)H-Index: 9
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#1Ashok Dogamanti (Osmania University)
#2Pamula Chiranjeevi (Osmania University)H-Index: 1
Last. M. SarasijaH-Index: 5
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As part of an ongoing effort to develop new anti-tubercular agents, a series of novel indole-fused spirochromene hybrids (7a-l) were efficiently synthesized in excellent yields by the popular 'Fisher-Indole synthesis' approach. The structure elucidation of the target compounds was carried out by different spectral techniques including 1H-NMR, 13C-NMR, ESI Mass, and FTIR analysis. Additionally, the proposed structure of 7i was proved by single-crystal X-ray analysis. These compounds (7a-l) were s...
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#1Dongamanti Ashok (Osmania University)H-Index: 9
#2M. Ram Reddy (Osmania University)H-Index: 2
Last. M. SarasijaH-Index: 5
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A series of new 3-(5-methyl-1-aryl-1H-1,2,3-triazol-4-yl)-1-phenyl-1H-pyrazole-4-carbaldehydes 4(a–g) and their benzimidazole derivatives 6(a–g) were synthesized under both conventional and microwave irradiation methods. However, we successfully achieved good yields in shorter reaction times under microwave irradiation. All the synthesized scaffolds were characterized by 1H NMR, 13C NMR, IR and mass spectral analyses. The synthesized compounds have been evaluated as potential antiproliferative a...
2 CitationsSource
#1Ravinder Dharavath (Osmania University)H-Index: 2
#2Nalaparaju Nagaraju (Osmania University)H-Index: 2
Last. G. Prashanthi (Saint Mary's College of California)H-Index: 1
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Coumarin-based 1,4-disubstituted 1,2,3-triazole derivatives were synthesized using a highly efficient, eco-friendly protocol via a copper(I)-catalyzed click reaction between various substituted arylazides and terminal alkynes. The synthetic route was easy to access and gave excellent yields under microwave irradiation conditions compared to the conventional heating route. The structures of all the compounds were characterized by IR, 1H NMR, 13C NMR spectroscopy and mass spectrometry. All the syn...
4 CitationsSource
#1Dongamanti Ashok (Osmania University)H-Index: 9
#2M. Ram Reddy (Osmania University)H-Index: 2
Last. M. SarasijaH-Index: 5
view all 6 authors...
Source
#1Dongamanti Ashok (Osmania University)H-Index: 9
#2Katta Ramakrishna (Osmania University)H-Index: 1
Last. M. SarasijaH-Index: 5
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Source
#1Dongamanti AshokH-Index: 9
Last. M. SarasijaH-Index: 5
view all 6 authors...
Source
#1Dongamanti Ashok (Osmania University)H-Index: 9
#2E. V. L. MadhuriH-Index: 1
Last. M. Sarasija (Satavahana University)H-Index: 5
view all 3 authors...
1 CitationsSource