Matthew S. Panizzon
University of California, San Diego
Internal medicineEndocrinologyDevelopmental psychologyDemographyPsychologyHeritabilityTwin studyNeuroscienceCognitionYoung adultDiseaseMiddle ageCerebral cortexCognitive impairmentAudiologyGenetic variationClinical psychologyGenetic correlationMedicineBiologyEpisodic memory
177Publications
35H-index
4,513Citations
Publications 169
Newest
#1Daniel E. Gustavson (VUMC: Vanderbilt University Medical Center)H-Index: 3
#2Jeremy A. Elman (University of California, Berkeley)H-Index: 15
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 13 authors...
Objective: Test the hypothesis that individual differences in episodic memory and verbal fluency in cognitively normal middle-aged adults will predict progression to amnestic MCI after 6 years. Method: The analysis sample included 842 male twins who were cognitively normal at baseline (M=56 years), completed measures of episodic memory and verbal fluency at baseline and again 6 years later (M=62 years). Results: Poor episodic memory predicted progression to both amnestic MCI (OR=4.42, 95% CI [2....
1 CitationsSource
#1William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
#2Matthew S. Panizzon (UCSD: University of California, San Diego)H-Index: 35
Last. Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
view all 14 authors...
Abstract Locus coeruleus (LC) tau accumulation begins early. Targeting LC (dys)function might improve early identification for Alzheimer’s disease (AD) risk. Pupillary responses during cognitive tasks are driven by the LC and index cognitive effort. Despite equivalent task performance, adults with mild cognitive impairment (MCI) have greater pupil dilation/effort during digit span than cognitively normal (CN) individuals. We hypothesized that AD polygenic risk scores (AD-PRSs) would be associate...
9 CitationsSource
#1Daniel E. Gustavson (UCSD: University of California, San Diego)H-Index: 16
#2Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 9 authors...
Source
#1Susan E. Luczak (SC: University of Southern California)H-Index: 20
#2Christopher R. Beam (SC: University of Southern California)H-Index: 11
Last. Margaret Gatz (SC: University of Southern California)H-Index: 96
view all 5 authors...
Source
#1Carol E. Franz (UCSD: University of California, San Diego)H-Index: 48
#2Richard L. Hauger (UCSD: University of California, San Diego)H-Index: 77
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 5 authors...
Source
#1Marianna Gasperi (UCSD: University of California, San Diego)H-Index: 4
#2John N. Krieger (UW: University of Washington)H-Index: 76
Last. Niloofar Afari (UCSD: University of California, San Diego)H-Index: 34
view all 6 authors...
Abstract Objective To evaluate the genetic and environmental relationship among prostatitis and other urological conditions, including benign prostatic hyperplasia (BPH) and prostate cancer (CaP), a classical twin design and biometric modeling was used. While prostatitis—characterized by pain and voiding symptoms, no clear etiology, and functional and quality of life impairments—co-occurs with other urinary conditions, the degree of shared overlapping etiologic processes among them remains uncle...
1 CitationsSource
#1Daniel E. Gustavson (UCSD: University of California, San Diego)H-Index: 16
#2Matthew S. Panizzon (UCSD: University of California, San Diego)H-Index: 35
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 9 authors...
Source
#1Jeremy A. ElmanH-Index: 15
#2Matthew S. PanizzonH-Index: 35
Last. William S. KremenH-Index: 70
view all 7 authors...
Source
#1Edith Hofer (Medical University of Graz)H-Index: 28
Last. Sudha SeshadriH-Index: 114
view all 99 authors...
Cortical thickness, surface area and volumes (MRI cortical measures) vary with age and cognitive function, and in neurological and psychiatric diseases. We examined heritability, genetic correlations and genome-wide associations of cortical measures across the whole cortex, and in 34 anatomically predefined regions. Our discovery sample comprised 22,822 individuals from 20 cohorts within the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium and the United Kingdom B...
18 CitationsSource
#1Mark Sanderson-Cimino (UCSD: University of California, San Diego)H-Index: 6
#2Matthew S. Panizzon (UCSD: University of California, San Diego)H-Index: 35
Last. William S. Kremen (UCSD: University of California, San Diego)H-Index: 70
view all 9 authors...
OBJECTIVE: Processing Speed (PS) is an important domain in cognitive aging that is characterized by multiple related but nonidentical abilities. Few studies have directly investigated the relationships among PS measures, and none have used genetically informed methods. In this study, we examined the relationship between measures of PS at up to two time points during middle age. METHOD: We examined data from 1,262 middle-aged men when the sample was at a mean age of 56 and a mean age 62 years. Pa...
1 CitationsSource