Louis-Ferdinand Lespine
University of Liège
OffspringInternal medicineEndocrinologyDevelopmental psychologyPsychologyPsychomotor learningNeuroscienceReceptorPhysical exerciseSensitizationReactivity (psychology)SalineFallypride18F-fallyprideAddictive drugsBehavioral testingPharmacological treatmentDrugs of abuseDevelopmental stageC57bl 6jWheel runningCocaine seekingConditioned place preferenceSubstance abuseAnesthesiaPhysiologyDopamine receptor D2ConditioningGestationDopamineTerm (time)MedicinePhysical medicine and rehabilitation
18Publications
3H-index
20Citations
Publications 21
Newest
#2Ezio TirelliH-Index: 24
#2Ezio TirelliH-Index: 24
#2Ezio TirelliH-Index: 24
#2Ezio TirelliH-Index: 24
#2Ezio TirelliH-Index: 24
#1Guillaume Becker (University of Liège)H-Index: 8
#2Louis-Ferdinand Lespine (University of Liège)H-Index: 3
Last. Alain Plenevaux (University of Liège)H-Index: 28
view all 8 authors...
Wheel-running exercise in laboratory rodents (animal model useful to study the neurobiology of aerobic exercise) decreases behavioral markers of vulnerability to addictive properties of various drugs of abuse including cocaine. However, neurobiological mechanisms underpinning this protective effect are far from being fully characterized and understood. Here, 28-day-old female C57BL/6J mice were housed with (n=48) or without (n=48) a running wheel for 6 weeks before being tested for acute locomot...
Source
#1Louis-Ferdinand Lespine (University of Liège)H-Index: 3
#2Ezio Tirelli (University of Liège)H-Index: 24
Abstract Wheel-running in rodents can mitigate addiction-related effects of drugs of abuse like cocaine. However, conditioned place preference (CPP) experiments have reported conflicting results, a situation warranting further studies. Our purpose was to test whether wheel-running exercise during adolescence could impact the formation and long-term retention of CPP to cocaine in mice. Male C57BL/6 J mice were individually housed either with (n = 32) or without (n = 32) a running wheel from the a...
Source
#1Louis-Ferdinand Lespine (University of Liège)H-Index: 3
#2Alain Plenevaux (University of Liège)H-Index: 28
Last. Ezio Tirelli (University of Liège)H-Index: 24
view all 3 authors...
Abstract While animal research has consistently reported preventive effects of exercise against drug abuse vulnerability, little is known about the influence of the developmental stage during which exercise is displayed on addictive drugs responsiveness. This study aimed to determine whether prenatal exercise could attenuate acute cocaine reactivity and psychomotor sensitization in youth offspring. We used a split-plot factorial design where C57BL/6 J females were randomly assigned into sedentar...
Source
#2Alain PlenevauxH-Index: 28
Last. Ezio TirelliH-Index: 24
view all 3 authors...
Source
#1Louis-Ferdinand Lespine (University of Liège)H-Index: 3
#2Ezio Tirelli (University of Liège)H-Index: 24
Wheel-running in rodents can mitigate addiction-related effects of drugs of abuse like cocaine. However, experiments using conditioned place preference (CPP) are conflicting, warranting further studies. Our purpose was to test whether wheel-running during adolescence could impact the formation and long-term retention of CPP to cocaine in mice. Male C57BL/6J mice were individually housed either with (n=32) or without (n=32) a running wheel from the age of 35 days. Behavioral testing began 3 weeks...
Source
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