Beau M. Ances
Washington University in St. Louis
Internal medicineNeuropsychologyPathologyMagnetic resonance imagingOncologyPsychologyCerebral blood flowNeuroscienceCognitionNeurocognitiveImmunologyDiseaseDementiaWhite matterHuman immunodeficiency virus (HIV)Alzheimer's diseaseNeuroimagingResting state fMRIMedicineBiomarker (medicine)
Publications 351
#1Julie K. WischH-Index: 6
#2Catherine M. RoeH-Index: 1
Last. Beau M. AncesH-Index: 60
view all 10 authors...
#1Brendan P. Lucey (WashU: Washington University in St. Louis)H-Index: 17
#2Julie K. Wisch (WashU: Washington University in St. Louis)H-Index: 6
Last. Beau M. Ances (WashU: Washington University in St. Louis)H-Index: 60
view all 11 authors...
Sleep monitoring may provide markers for future Alzheimer's disease; however, the relationship between sleep and cognitive function in preclinical and early symptomatic Alzheimer's disease is not well understood. Multiple studies have associated short and long sleep times with future cognitive impairment. Since sleep and the risk of Alzheimer's disease change with age, a greater understanding of how the relationship between sleep and cognition changes over time is needed. In this study, we hypot...
#1Binyin Li (Harvard University)H-Index: 11
#2Ikbeom Jang (Harvard University)H-Index: 3
view all 9 authors...
Given the difficulty in factoring out typical age effects from subtle Alzheimer's disease (AD) effects on brain structure, identification of very early, as well as younger preclinical "at-risk" individuals has unique challenges. We examined whether age-correction procedures could be used to better identify individuals at very early potential risk from adults who did not have any existing cognitive diagnosis. First, we obtained cross-sectional age effects for each structural feature using data fr...
#2Alice Y. Zhou (WashU: Washington University in St. Louis)H-Index: 10
#1Rebecca Bollinger (WashU: Washington University in St. Louis)H-Index: 1
#2Audrey Keleman (WashU: Washington University in St. Louis)H-Index: 1
Last. John C. Morris (WashU: Washington University in St. Louis)H-Index: 204
view all 12 authors...
Introduction null Progression to symptomatic Alzheimer disease (AD) occurs slowly over a series of preclinical stages. Declining functional mobility may be an early indicator of loss of brain network integration and may lead to an increased risk of experiencing falls. It is unknown whether measures of functional mobility and falls are preclinical markers of AD. The purpose of this study is to examine (1) the relationship between falls and functional mobility with AD biomarkers to determine when ...
#1Leah H. Rubin (Johns Hopkins University)H-Index: 38
#2Beau M. Ances (WashU: Washington University in St. Louis)H-Index: 60
Background null The relationship between HIV infection, the functional organization of the brain, cognitive impairment, and aging remains poorly understood. Understanding disease progression over the lifespan is vital for the care of people living with HIV (PLWH). null Setting null Virologically suppressed PLWH (n=297) on combination antiretroviral therapy and 1509 controls were evaluated. PLWH were further classified as cognitively normal (CN) or impaired (CI) based on neuropsychological testin...
#1Anne M. Fagan (WashU: Washington University in St. Louis)H-Index: 92
#2Rachel L. Henson (WashU: Washington University in St. Louis)H-Index: 3
Last. Bradley T. Christian (UW: University of Wisconsin-Madison)H-Index: 38
view all 34 authors...
Summary null null Background null Due to trisomy of chromosome 21 and the resultant extra copy of the amyloid precursor protein gene, nearly all adults with Down syndrome develop Alzheimer's disease pathology by the age of 40 years and are at high risk for dementia given their increased life expectancy compared with adults with Down syndrome in the past. We aimed to compare CSF biomarker patterns in Down syndrome with those of carriers of autosomal dominant Alzheimer's disease mutations to enhan...
#1Yves Carlo Pinpin (WashU: Washington University in St. Louis)
#2Erin R. Foster (WashU: Washington University in St. Louis)H-Index: 13
Last. Beau M. Ances (WashU: Washington University in St. Louis)H-Index: 60
view all 3 authors...
#1Victoria Fleming (UW: University of Wisconsin-Madison)
#2Brianna Piro-Gambetti (UW: University of Wisconsin-Madison)H-Index: 2
Last. Charles M. Laymon (University of Pittsburgh)H-Index: 23
view all 14 authors...
Abstract null null Adults with Down syndrome (DS) are at risk for Alzheimer's disease. Despite sharing trisomy 21, however, there is variability in the age of disease onset. This variability may mean that other factors, such as lifestyle, influence cognitive aging and disease timing. The present study assessed the association between everyday life physical activity using an actigraph accelerometer and cognitive functioning and early Alzheimer's disease pathology via positron emission tomography ...
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